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Understanding Lung Cancer Screening: When is Surgery the Right Choice?

Understanding Lung Cancer Screening

Lung cancer remains one of the most common and deadly cancers worldwide, but early detection
can make a significant difference. Screening plays a crucial role in finding lung cancer at an early,
more treatable stage. However, not everyone with a positive screening result will require surgery.
Determining when surgery is necessary depends on several factors, including the cancer’s stage,
location, and the patient’s overall health. Here’s an in-depth look at how lung cancer screening
works and when surgery becomes the recommended path.

What is Lung Cancer Screening?
Lung cancer screening is a preventive measure that aims to detect lung cancer in its early stages, even before symptoms appear. This is typically done using a low-dose computed tomography (LDCT) scan, which takes detailed images of the lungs with minimal radiation exposure. LDCT is currently the preferred method because it’s effective at identifying small nodules or abnormal areas in the lungs that might indicate cancer.
Screening is usually recommended for individuals who have a higher risk of lung cancer, which may include:
• Adults aged 50–80 with a history of smoking
• Current or former smokers who quit within the last 15 years
• Those with a pack-year history of 20 or more (meaning they smoked one pack a day for 20 years or two packs a day for 10 years)
If you fall into one of these categories, your doctor may suggest regular screening to detect any abnormalities as early as possible.


What Happens if a Lung Nodule is Detected?
A positive screening result does not automatically mean a person has lung cancer. Many lung nodules found on scans are benign and require only monitoring. If a nodule is detected, additional imaging tests or a biopsy may be performed to determine whether it’s cancerous. Based on the nodule’s size, appearance, and any associated risk factors, the doctor will recommend a course of action.


When Surgery is Recommended for Lung Cancer
If lung cancer is confirmed, treatment options are based on the stage and extent of the disease. Surgery is most commonly recommended for early-stage lung cancer (typically Stage I and sometimes Stage II), when the cancer is confined to a specific area and hasn’t spread. Let’s explore some scenarios where surgery might be advised:

  1. Early-Stage Cancer (Stage I and II)
    o Why Surgery is Chosen: In early-stage lung cancer, the tumor is localized, making it possible to remove all visible cancer cells with surgery. Removing the affected lung tissue can prevent the cancer from spreading and improve long-term outcomes.
    o Types of Surgery: Common surgical options include lobectomy (removal of a lung lobe), segmentectomy (removal of part of a lobe), and, in some cases, wedge resection (removal of a small portion of lung tissue). The choice depends on the size and location of the tumor.
  2. Localized Tumors Without Lymph Node Involvement
    o Why Surgery is Chosen: If the cancer is localized to one area without spreading to the lymph nodes, surgery can be highly effective. Removing the tumor may prevent the disease from advancing, and additional treatments like chemotherapy may not be necessary.
    o Types of Surgery: In these cases, a lobectomy is often the preferred method as it removes the entire affected lobe, providing a clear margin around the tumor.
  3. Certain Cases of Stage II and III Lung Cancer
    o Why Surgery May Be Chosen: In some cases of Stage II or III lung cancer, where there’s limited lymph node involvement, surgery may be part of a combined treatment plan. Surgery can sometimes follow chemotherapy or radiation to shrink the tumor and make it easier to remove.
    o Types of Surgery: For larger tumors, more extensive surgery such as a pneumonectomy (removal of the entire lung) may be necessary, although this is less common. The decision for surgery in these stages is made carefully, considering the patient’s health and the cancer’s specifics.
  4. Minimally Invasive Surgery for Early Detection Cases
    o Why Surgery is Chosen: When lung cancer is detected at a very early stage, minimally invasive surgery can be an excellent option. Techniques like Video-Assisted Thoracoscopic Surgery (VATS) or robotic-assisted surgery allow for the removal of tumors with small incisions, which reduces recovery time and potential complications.
    o Types of Surgery: Minimally invasive options may include wedge resection or segmentectomy, particularly if the tumor is small and isolated.
    When Surgery Might Not Be the Best Option
    While surgery is a valuable tool in early-stage lung cancer treatment, it’s not always the best choice, especially in the following situations:
  5. Advanced-Stage Cancer (Stage IV)
    o For advanced-stage lung cancer that has spread to other organs, surgery is usually not recommended because it won’t eliminate all cancerous cells. Treatment in these cases typically involves chemotherapy, targeted therapy, radiation, or immunotherapy to control the disease and manage symptoms.
  6. Poor Health or Lung Function
    o For patients with compromised lung function or other significant health issues, surgery might be too risky. In such cases, alternative treatments like radiation therapy, stereotactic body radiotherapy (SBRT), or targeted therapies may be considered to address the cancer without invasive surgery.
  7. Metastasis to Lymph Nodes or Other Organs
    o When cancer has spread to multiple lymph nodes or distant organs, a surgical cure is unlikely. Instead, systemic therapies like chemotherapy or immunotherapy are preferred to treat cancer throughout the body.
    What to Expect if Surgery is Necessary
    If surgery is deemed the best option, here’s what you can expect:
  8. Pre-Surgery Preparation
    o Patients typically undergo preoperative testing, including imaging, pulmonary function tests, and blood work, to ensure they’re healthy enough for surgery. Quitting smoking, if applicable, and engaging in breathing exercises can also improve outcomes.
  9. Types of Surgery and Recovery
    o Most lung cancer surgeries are performed under general anesthesia and may involve an inpatient hospital stay. Recovery times vary based on the type of surgery, with minimally invasive surgeries generally allowing for a faster return to normal activities.
  10. Post-Surgery Follow-Up
    o After surgery, regular follow-up appointments are essential to monitor for recurrence. Imaging tests and lung function assessments help ensure the cancer hasn’t returned and provide a baseline for ongoing health.

Final Thoughts
Lung cancer screening can be a lifesaving tool, especially for those at higher risk, as it enables early detection and timely treatment. When caught early, surgery can offer an effective path to removing cancer and reducing the likelihood of recurrence. However, surgery is just one part of the treatment landscape, and the decision to undergo surgery depends on many factors, including the cancer’s stage, location, and the patient’s overall health.
If you or a loved one is facing a lung cancer diagnosis, discussing screening results and treatment options with a thoracic surgeon and an oncology team can help you make the most informed choice. Remember, every case is unique, and a personalized approach is key to finding the best path forward.

Understanding Lung Cancer Screening

Picture of Marco Scarci
Marco Scarci

Highly respected consultant thoracic surgeon based in London. He is renowned for his expertise in keyhole surgery, particularly in the treatment of lung cancer and pneumothorax (collapsed lung). He also specialises in rib fractures, hyperhidrosis (excessive sweating), chest wall deformities and emphysema.

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